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Article

Histological and molecular characterization of intrahepatic bile duct cancers suggests an expanded definition of perihilar cholangiocarcinoma.

HPB : the official journal of the International Hepato Pancreato Biliary Association - 1 Feb 2019

Akita Masayuki, Sofue Keitaro, Fujikura Kohei, Otani Kyoko, Itoh Tomoo, Ajiki Tetsuo, Fukumoto Takumi, Zen Yoh

Abstract excerpt

BACKGROUND: Growing evidence has suggested that intrahepatic cholangiocarcinoma (iCCA) can be classified into small- and large-duct types. The present study aimed to elucidate how large-duct iCCA is similar and dissimilar to perihilar cholangiocarcinoma (pCCA). METHODS: The study cohort consisted of iCCA (n = 58) and pCCA (n = 44). After iCCA tumors were separated into small- (n = 36) and large-duct (n = 22)...

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Aged
Aged, 80 and over
Bile Duct Neoplasms
Biomarkers, Tumor
Gene Amplification

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

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Identifiers

PMID: 30170977
DOI: 10.1016/j.hpb.2018.07.021

Genes

BAP1
IDH1
MDM2
SMAD4

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