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Article

Inherited prion disease caused by the V210I mutation: transmission to transgenic mice.

Neurology - 26 Dec 2001

Mastrianni J A, Capellari S, Telling G C, Han D, Bosque P, Prusiner S B, DeArmond S J

Abstract excerpt

OBJECTIVE: To describe the clinical and neuropathologic profile and determine the strain characteristics of familial Creutzfeldt-Jakob disease (fCJD) caused by a point mutation of the PRNP gene at codon 210 that results in a valine-to-isoleucine substitution in the prion protein (PrP). METHODS: T...

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Identifiers

PMID: 11756597
DOI: 10.1212/wnl.57.12.2198

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11756597-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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