Article
Mutations in PilZ domains of newly discovered bacterial β-(1,3;1,4)-mixed linkage glucan synthases modulate polysaccharide production.
Carbohydrate polymers - 15 May 2026
Saldivar Rebecka Karmakar, Chang Shu-Chieh Susie, Rajkumari Sheileza, Pratama Rico A, Lin Yen-Ting, Kao Mu-Rong, Divne Christina, Ni Chi-Kung, Hsieh Yves S Y
Abstract excerpt
β-(1,3;1,4)-Mixed linkage glucans (MLGs) are linear homopolysaccharides composed of β-1,4-linked glucose oligomers interconnected by β-1,3 linkages. While previous studies have characterised MLG synthases from Romboutsia ilealis and Clostridium ventriculi, the broader diversity of these enzymes remains underexplored. To expand the repertoire of bacterial MLG synthases, nine glycosyltransferase family 2 (GT2)...
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