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Article

Glucoamylase: structure/function relationships, and protein engineering.

Biochimica et biophysica acta - 29 Dec 2000

Sauer J, Sigurskjold B W, Christensen U, Frandsen T P, Mirgorodskaya E, Harrison M, Roepstorff P, Svensson B

Abstract excerpt

Glucoamylases are inverting exo-acting starch hydrolases releasing beta-glucose from the non-reducing ends of starch and related substrates. The majority of glucoamylases are multidomain enzymes consisting of a catalytic domain connected to a starch-binding domain by an O-glycosylated linker region. Three-dimensional structures have been determined of free and inhibitor complexed glucoamylases from Aspergillus...

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PMID: 11150611
DOI: 10.1016/s0167-4838(00)00232-6

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