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Hybrid genotype I and II ASFV D250R deletions confer protection against parental and genotype II strains and elicit potent immune response.

Emerging microbes & infections - 1 Dec 2026

Jia Xiaoying, Li Nan, Sun Xuefei, Ke Junnan, Zheng Min, Wang Fengjie, Yue Huixian, Hao Zhuo, Jiang Yiqian, Li Qixuan, Chen Teng, Qi Yu, Wang Ying, Zhang Shoufeng, Wang Shuchao, Hu Rongliang, Miao Faming, Zhang Yanyan

Abstract excerpt

African Swine Fever Virus (ASFV) continues to mutate uncontrollably, with outbreaks caused by genotype II strains inflicting substantial economic losses on the global swine industry. Currently, a more virulent recombinant strain, combining genotype I and II, is spreading across China, Russia and Vietnam, exacerbating the severity of the epidemic. The development of safe and effective ASFV vaccines is therefore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41821422
DOI: 10.1080/22221751.2026.2640697
PMCID: PMC12990284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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