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Co-Deletion of A238L and EP402R Genes from a Genotype IX African Swine Fever Virus Results in Partial Attenuation and Protection in Swine.

Viruses - 13 Sept 2022

Abkallo Hussein M, Hemmink Johanneke D, Oduor Bernard, Khazalwa Emmanuel M, Svitek Nicholas, Assad-Garcia Nacyra, Khayumbi Jeremiah, Fuchs Walter, Vashee Sanjay, Steinaa Lucilla

Abstract excerpt

African swine fever virus (ASFV) is the causative agent of African swine fever (ASF), resulting in up to 100% mortality in pigs. Although endemic in most sub-Saharan African countries, where all known ASFV genotypes have been reported, the disease has caused pandemics of significant economic impact in Eurasia, and no vaccines or therapeutics are available to date. In endeavors to develop live-attenuated vaccines...

Topics

African Swine Fever
African Swine Fever Virus
Animals
Genotype
Sus scrofa
Swine
Vaccines, Attenuated
Viral Proteins
Viral Vaccines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36146830
DOI: 10.3390/v14092024
PMCID: PMC9501025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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