Evaluation of An I226R and A137R deletion mutant from a genotype I/II recombinant African swine fever virus strain as a live attenuated vaccine in pigs.

doi:10.1186/s13567-026-01827-6

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Evaluation of An I226R and A137R deletion mutant from a genotype I/II recombinant African swine fever virus strain as a live attenuated vaccine in pigs.

Veterinary research - 28 Aug 2026

Zhang Han, Li Qixuan, Li Nannan, Wang Ying, Hou Tianying, Wang Hongliang, Hu Rongliang, Zhang Yanyan, Zhang Shoufeng, Miao Faming

Abstract excerpt

The emergence of highly lethal genotype I/II recombinant African swine fever virus (ASFV) strains in China has rendered existing genotype II-based live attenuated vaccines ineffective, underscoring the urgent need for novel vaccine candidates. Although single-gene deletions of A137R or I226R have shown promise against genotype II strains, their efficacy and safety in the context of recombinant strains remain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to African Swine Fever
Share to African Swine Fever Virus
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Swine

Share to Vaccines, Attenuated

Share to Viral Vaccines

Source

Open in PubMed Open full text

Identifiers

PMID: 42665846
DOI: 10.1186/s13567-026-01827-6
PMCID: PMC13525649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.