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The attenuated African swine fever vaccine HLJ/18-7GD provides protection against emerging prevalent genotype II variants in China.

Emerging microbes & infections - 1 Dec 2024

Wang Zilong, Zhang Jiwen, Li Fang, Zhang Zhenjiang, Chen Weiye, Zhang Xianfeng, Sun Encheng, Zhu Yuanmao, Liu Renqiang, He Xijun, Bu Zhigao, Zhao Dongming

Abstract excerpt

Genetic changes have occurred in the genomes of prevalent African swine fever viruses (ASFVs) in the field in China, which may change their antigenic properties and result in immune escape. There is usually poor cross-protection between heterogonous isolates, and, therefore, it is important to test the cross-protection of the live attenuated ASFV vaccines against current prevalent heterogonous isolates. In this...

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Identifiers

PMID: 38164797
DOI: 10.1080/22221751.2023.2300464
PMCID: PMC10810661

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