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Article

Genotype II Live-Attenuated ASFV Vaccine Bearing 24 Genes Deletion in 3 Independent Regions Is Able to Provide Complete Protection Against Homologous Lethal Challenge.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 15 Sept 2026

Xu Fan, Dang Wen, Du Yu, Li Tao, Liu Huanan, Shi Zhengwang, Tian Hong, He Jijun, Zheng Haixue

Abstract excerpt

African swine fever (ASF) is an acute, febrile, and highly contagious infectious disease of swine with the etiological agent of African swine fever virus (ASFV). The mortality rate of virulent strains is as high as 100%. Strengthening biosafety is so far the most effective way to prevent and control ASF. Therefore, it is urgent to develop a safe and effective vaccine. In this study, a Genotype II live-attenuated...

Read the complete abstract on PubMed

Topics

Animals
African Swine Fever Virus
African Swine Fever
Vaccines, Attenuated
Viral Vaccines

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Swine

Gene Deletion

Genotype

Virulence

Antibodies, Viral

Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 42684801
DOI: 10.1096/fj.202601491R
PMCID: PMC13537467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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