Article
Familial genetic risk for posttraumatic stress disorder: Associations with clinical features.
Journal of traumatic stress - 1 Jun 2026
Amstadter Ananda B, Abrahamsson Linda, Hart James E, Sundquist Jan, Kendler Kenneth S, Sundquist Kristina
Abstract excerpt
In the present study, the novel family genetic risk score (FGRS) method, a reliable quantification of latent genetic risk, was applied to posttraumatic stress disorder (PTSD) to examine associations between genetic liability and clinical features of PTSD among 3,097,180 individuals in the Swedish national registries. FGRS was calculated based on lifetime PTSD status for first- through fifth-degree relatives and...
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