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Article

BDNF Val66Met polymorphism modulates early TMS-EEG plasticity and rTMS efficacy in patients with anterior circulation ischemic stroke.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 12 Mar 2026

Lin Jingyuan

Abstract excerpt

OBJECTIVE: This study aimed to explore whether the BDNF Val66Met polymorphism influences early cortical plasticity, as measured by TMS-EEG, and its impact on rTMS therapy response in anterior-circulation ischemic stroke, with outcomes evaluated at day 14 and day 90 post-stroke. METHODS: We retrospectively analyzed 200 patients genotyped for BDNF Val66Met: Val/Val (n = 102), Val/Met (n = 79), and Met/Met (n = 19)....

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PMID: 41814041
DOI: 10.1007/s10072-026-08948-y

Genes

BDNF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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