Article
Val66Met BDNF Polymorphism Implies a Different Way to Recover From Stroke Rather Than a Worse Overall Recoverability.
Neurorehabilitation and neural repair - 1 Jan 2016
Di Pino Giovanni, Pellegrino Giovanni, Capone Fioravante, Assenza Giovanni, Florio Lucia, Falato Emma, Lotti Fiorenza, Di Lazzaro Vincenzo
Abstract excerpt
In search for individualized predictors of stroke recovery, the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) is attracting great interest, because it has a negative impact on neurotrophin function. Since stroke recovery relies on brain plastic processes, on which BDNF is permissive, the dominant thought is in favor of a worse recovery in Met carriers. Conversely, we suggest that Met...
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