GGPS1 Promoter Variant (rs3806394) Is Associated With Larger Simple Renal Cysts via Reduced GGPPS Expression.

Abstract excerpt

Objective: We are aimed at investigating the association between the size of simple renal cyst (SRC) and the expression of geranylgeranyl pyrophosphate synthase (GGPPS), which can induce renal cyst formation after its deletion. Methods: Seventy-seven patients who received renal cyst decortication were enrolled. Clinical characteristics and tissue sections were collected. We used immunohistochemistry and...

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