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Identification of the pivotal role of SPP1 in kidney stone disease based on multiple bioinformatics analysis

11 Jan 2022

Abstract excerpt

BACKGROUND: Kidney stone disease (KSD) is a multifactorial disease involving both environmental and genetic factors, whose pathogenesis remains unclear. This study aims to explore the hub genes related to stone formation that could serve as potential therapeutic targets. METHODS: Based on the GSE73680 dataset with 62 samples, differentially expressed genes (DEGs) between Randall's plaque (RP) tissues and normal...

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Share to Kidney Stones and Urolithiasis Treatments
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35016690
DOI: 10.1186/s12920-022-01157-4

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