Article
Application of Long-Read Sequencing for Genotyping, Epigenetic Profiling and Surveillance of Yersinia pestis Isolates from Natural Foci and Disease Outbreaks in Central Asia.
Vector borne and zoonotic diseases (Larchmont, N.Y.) - 1 Jun 2026
Abdirassilova Aigul A, Yessimseit Duman T, Rysbekova Altyn K, Kassenova Altynai K, Abdeliyev Beсk Z, Zhumadilova Zauresh B, Tokmurziyeva Gulnara Zh, Dikhanbayev Arnat S, Agzam Sanzhar D, Motin Vladimir L, Reva Oleg N
Abstract excerpt
INTRODUCTION: This study explores the application of long-read sequencing technologies for genotyping, epigenetic profiling, and epidemiological monitoring of Yersinia pestis isolates obtained from natural foci in Central Asia and previous zoonotic outbreaks. METHODS: Computational tools for genome assembly and genotyping were developed, enabling high-precision identification of both chromosomal and plasmid...
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