Article
Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity.
Nature genetics - 1 Dec 2010
Morelli Giovanna, Song Yajun, Mazzoni Camila J, Eppinger Mark, Roumagnac Philippe, Wagner David M, Feldkamp Mirjam, Kusecek Barica, Vogler Amy J, Li Yanjun, Cui Yujun, Thomson Nicholas R, Jombart Thibaut, Leblois Raphael, Lichtner Peter, Rahalison Lila, Petersen Jeannine M, Balloux Francois, Keim Paul, Wirth Thierry, Ravel Jacques, Yang Ruifu, Carniel Elisabeth, Achtman Mark
Abstract excerpt
Plague is a pandemic human invasive disease caused by the bacterial agent Yersinia pestis. We here report a comparison of 17 whole genomes of Y. pestis isolates from global sources. We also screened a global collection of 286 Y. pestis isolates for 933 SNPs using Sequenom MassArray SNP typing. We conducted phylogenetic analyses on this sequence variation dataset, assigned isolates to populations based on maximum...
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