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Article

A field-deployable high-resolution SNP genotyping platform for rapid surveillance of Yersinia pestis.

Virulence - 1 Dec 2026

Liu Ying, Huang Qiuying, Wu Yarong, Zheng Jiahao, Xu Mingzhu, Guo Liu, Liu Fang, Cui Mengnan, Guo Yan, Zuo Xiujuan, Li Jianyun, Wang Xin, Jing Huaiqi, Yang Ruifu, Cui Yujun, Li Qingge

Abstract excerpt

Yersinia pestis, the causative agent of plague, poses a persistent global health threat due to its rapid transmission and high mortality. To enable rapid, field-deployable surveillance, we developed a high-resolution, culture-independent genotyping assay for precise identification of Y. pestis lineages and sublineages. We curated and validated 25 canonical single nucleotide polymorphisms (canSNPs) to resolve 24...

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Identifiers

PMID: 42418343
DOI: 10.1080/21505594.2026.2700072
PMCID: PMC13348942

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