Article
Genome sequence of the deep-rooted Yersinia pestis strain Angola reveals new insights into the evolution and pangenome of the plague bacterium.
Journal of bacteriology - 1 Mar 2010
Eppinger Mark, Worsham Patricia L, Nikolich Mikeljon P, Riley David R, Sebastian Yinong, Mou Sherry, Achtman Mark, Lindler Luther E, Ravel Jacques
Abstract excerpt
To gain insights into the origin and genome evolution of the plague bacterium Yersinia pestis, we have sequenced the deep-rooted strain Angola, a virulent Pestoides isolate. Its ancient nature makes this atypical isolate of particular importance in understanding the evolution of plague pathogenicity. Its chromosome features a unique genetic make-up intermediate between modern Y. pestis isolates and its...
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