Article
Association between psychiatric disorders and irritable bowel syndrome: A bidirectional Mendelian randomization study.
Journal of affective disorders - 1 Jan 2025
Wang Fan, Liu Yi-Long, Jiang Chun-Hui, Wu Hong-Yu, Jin Jing, Sun Yu-Wei, He Zi-Xuan, Kang Le, Fang Xue
Abstract excerpt
OBJECTIVE: Previous studies have suggested that irritable bowel syndrome (IBS) is strongly associated with psychiatric disorders. However, it is unclear whether this association is causal, concomitant, or accidental. Thus, we performed Mendelian randomization (MR) analysis to evaluate the causal effects of several psychiatric disorders on IBS. METHODS: Summary data of genome-wide association studies (GWASs) were...
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