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Article

Causal relationship between major depressive disorder, anxiety disorder and constipation: a two-sample Mendelian randomization study.

BMC gastroenterology - 27 Nov 2024

Deng ZhiYu, Zeng XiaoYu, Wang HanYu, Bi Wei, Huang YuMei, Fu Hao

Abstract excerpt

BACKGROUND: Epidemiological and other studies have shown correlations among major depressive disorder (MDD), anxiety disorder (AXD) and constipation. However, no consensus has been reached regarding their interdependence and pathogenesis. Herein, we sought to further explore the causal associations between them. METHODS: Bidirectional two-sample Mendelian randomization (MR) analysis was performed to confirm the...

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Identifiers

PMID: 39592920
DOI: 10.1186/s12876-024-03526-y
PMCID: PMC11600672

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