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Article

Causal association between depression and constipation: A bidirectional two-sample Mendelian randomization study.

Medicine - 6 Dec 2024

Guan Xiaoyan, Ni Qianyang, Zhai Ziqi, Sun Yupei, Zhang Yan

Abstract excerpt

There is currently insufficient research on the causal relationship between depression and constipation. This study aims to provide clear evidence for the positive and negative causal relationship between depression and constipation through bidirectional two-sample Mendelian randomization (MR) analysis. MR is a statistical method used to evaluate the credible causal relationship between exposure and outcomes. In...

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Identifiers

PMID: 39654229
DOI: 10.1097/MD.0000000000040788
PMCID: PMC11630922

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