Article
Plasma proteomic profiles of lung volume-based phenotypes in tobacco-exposed individuals without spirometric chronic obstructive pulmonary disease.
Annals of the American Thoracic Society - 1 Jul 2026
Zeng Siyang, Guo Claire, Pratte Katherine A, Luo Gang, Bowler Russell P, Arjomandi Mehrdad
Abstract excerpt
BACKGROUND: Among individuals with a history of smoking but preserved spirometry (tobacco exposed with preserved spirometry, or TEPS), lung volume-based stratification identifies 2 phenotypes at increased risk for chronic obstructive pulmonary disease (pre-COPD): those with a relatively elevated total lung capacity ([TLC]high) and those with a relatively elevated functional residual capacity-to-TLC ratio...
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