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Article

Associations of social isolation and loneliness with the risk of adult-onset asthma: A prospective cohort and mendelian randomization study.

Chronic respiratory disease - 1 Jan 2026

Zhang Juanjuan, Li Yuqian, Sun Xiangdong, An Ruiqi, Zhang Hongjie, Gong Jianping, Zhang Yuanda, Li Yijue, Gu Yanfeng, Xia Yang

Abstract excerpt

BackgroundDespite proposed aetiological mechanisms involving stress-induced inflammation and behaviour, population-level evidence linking social isolation and loneliness to asthma is lacking. Therefore, we aimed to examine the associations of social isolation, loneliness, and genetic predisposition with asthma risk in middle-aged and older adults, and to quantify the contribution of various risk factors.MethodsA...

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Identifiers

PMID: 41774051
DOI: 10.1177/14799731261422727
PMCID: PMC12957583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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