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Small RNA directed DNA methylation by Pol IV and Pol V maintains immune homeostasis in soybean.

The Plant cell - 3 Apr 2026

Zhang Ziming, Sun Hongda, Wu Mingwei, Chen Jinfeng, Wang Yuan

Abstract excerpt

Transposable element (TE) insertions and DNA methylation variability are frequently associated with defense-related genes in Arabidopsis thaliana. Pathogen infections trigger genome-wide DNA demethylation, suggesting a critical role for DNA methylation in immune regulation. However, the precise function of DNA methylation, as a host defense mechanism or a byproduct of pathogenesis, remains unclear, partly due to...

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PMID: 41773778
DOI: 10.1093/plcell/koag033

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