Back to search

Article

Construction of a solid Cox model for AML patients based on multiomics bioinformatic analysis

2021-09-16

Abstract excerpt

Acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy. The bone marrow (BM) microenvironment in AML plays an important role in leukemogenesis, drug resistance and leukemia relapse. In this study, we aimed to identify reliable immune-related biomarkers for AML prognosis by multiomics analysis. We obtained expression profiles from The Cancer Genome Atlas (TCGA) database and constructed a LA...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8733cc9b-3771-5264-bf40-de8693ebf696
DOI
10.1101/2021.09.15.460430
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Construction of a solid Cox model for AML patients based on multiomics bioinformatic analysisDOI 10.1101/2021.09.15.460430
Identification of an Immune-Related Gene Signature Based on Immunogenomic Landscape Analysis to Predict the Prognosis of Adult Acute Myeloid Leukemia PatientsSemantic proximity
Immune Infiltration-Related Genes Regulate the Progression of AML by Invading the Bone Marrow MicroenvironmentSemantic proximity
Immune infiltration-related genes regulate the progression of AML by invading the bone marrow microenvironment.Semantic proximity
Identification of a Mitochondria-Related Gene Signature to Predict the Prognosis in AMLSemantic proximity
Immune-related lncRNAs pairs prognostic score model for prediction of survival in acute myeloid leukemia patientsSemantic proximity
Identification and validation of hub genes and molecular classifications associated with chronic myeloid leukemiaSemantic proximity
Immune-related gene signature predicts clinical outcomes and immunotherapy response in acute myeloid leukemia.Semantic proximity
Identification of Molecular and Immune Prognostic Classifiers of Acute Myeloid LeukemiaSemantic proximity
Construction of an acute myeloid leukemia prognostic model based on m6A-related efferocytosis-related genesSemantic proximity
An Immunogenic Cell Death-Based Risk model Predicts Prognosis and Indicates Immune Infiltration Landscape in Acute Myeloid LeukemiaSemantic proximity
Identification and validation of lymphangiogenesis-related genes for predicting acute myeloid leukemia prognosis: insights from bulk RNA sequencing and single-cell RNA sequencing analyses.Semantic proximity
Identification of Tumor Antigens and Immune Subtypes of Acute Myeloid Leukemia for mRNA Vaccine DevelopmentSemantic proximity
Select a neighboring publication to make it the new centre.