Article
Epstein-Barr virus-associated gastric carcinoma: a distinct carcinoma of gastric phenotype by claudin expression profiling.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Aug 2009
Shinozaki Aya, Ushiku Tetsuo, Morikawa Teppei, Hino Rumi, Sakatani Takashi, Uozaki Hiroshi, Fukayama Masashi
Abstract excerpt
Epstein-Barr virus (EBV)-associated gastric carcinoma (GC) is a distinct subtype with characteristic clinicopathological features. To better characterize its cellular characteristics, 43 cases of EBV-associated GC, 68 cases of EBV-negative GC, and non-neoplastic gastric mucosa in adults and fetuses were examined immunohistochemically. We quantified the expression of the major tight-junction protein claudin (CLDN)...
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