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Article

Pan-cancer analysis of PDZK1IP1 reveals its role in tumorigenesis and tumor immunity: focused validation in thyroid carcinoma.

Hereditas - 27 Feb 2026

Geng Chenchen, Gao Xiaoqian, Le Yali, Zhu Shuzhen, Zhao Guanghui, Zhang Ping

Abstract excerpt

BACKGROUND: PDZK1IP1 is a membrane protein linked to inflammation and cancer, but its role in the tumor immune microenvironment is poorly understood. This study systematically investigated the oncogenic and immunological functions of PDZK1IP1 via a pan-cancer analysis, with experimental validation in thyroid carcinoma (THCA). METHODS: We conducted a comprehensive bioinformatic analysis of PDZK1IP1 using publicly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41761346
DOI: 10.1186/s41065-026-00662-1
PMCID: PMC13049858

Genes

PDZK1IP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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