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Article

Sensitive Next-Generation Sequencing Method Reveals Deep Genetic Diversity of HIV-1 in the Democratic Republic of the Congo.

Journal of virology - 15 Mar 2017

Rodgers Mary A, Wilkinson Eduan, Vallari Ana, McArthur Carole, Sthreshley Larry, Brennan Catherine A, Cloherty Gavin, de Oliveira Tulio

Abstract excerpt

As the epidemiological epicenter of the human immunodeficiency virus (HIV) pandemic, the Democratic Republic of the Congo (DRC) is a reservoir of circulating HIV strains exhibiting high levels of diversity and recombination. In this study, we characterized HIV specimens collected in two rural areas of the DRC between 2001 and 2003 to identify rare strains of HIV. The env gp41 region was sequenced and...

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Identifiers

PMID: 28077647
DOI: 10.1128/JVI.01841-16
PMCID: PMC5331799

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