Article
A cross-sectional study to characterize local HIV-1 dynamics in Washington, DC using next-generation sequencing.
Scientific reports - 6 Feb 2020
Gibson Keylie M, Jair Kamwing, Castel Amanda D, Bendall Matthew L, Wilbourn Brittany, Jordan Jeanne A, Crandall Keith A, Pérez-Losada Marcos
Abstract excerpt
Washington, DC continues to experience a generalized HIV-1 epidemic. We characterized the local phylodynamics of HIV-1 in DC using next-generation sequencing (NGS) data. Viral samples from 68 participants from 2016 through 2017 were sequenced and paired with epidemiological data. Phylogenetic and network inferences, drug resistant mutations (DRMs), subtypes and HIV-1 diversity estimations were completed....
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