Risk-stratified surveillance for individuals in the UK at high risk of developing pancreatic cancer: Outcomes from the European Registry of Hereditary Pancreatic Diseases (EUROPAC).

doi:10.1016/j.ejca.2026.116592

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Risk-stratified surveillance for individuals in the UK at high risk of developing pancreatic cancer: Outcomes from the European Registry of Hereditary Pancreatic Diseases (EUROPAC).

European journal of cancer (Oxford, England : 1990) - 26 Mar 2026

Hopley Phillip J, Peysner Ryan, Boughey Annabelle, Kewlani Bharti, Smith Andrew M, Aithal Guruprasad P, Oppong Kofi W, Finch-Jones Meg, Hamady Zaed, Athwal Tejinderjit S, Milburn James, Menon Shyam, Chapman Michael, Pereira Stephen P, Taylor Mark, Shingler Guy, Briggs Christopher, Ghaneh Paula, Costello Eithne, Greenhalf William, Halloran Christopher M

Abstract excerpt

BACKGROUND: Surveillance of individuals with a familial predisposition to pancreatic ductal adenocarcinoma (PDAC) is likely to increase overall survival. Our objective was to determine the impact of EUROPAC risk-stratification (Family Risk, FR), in such predisposed individuals. METHODS: Observational study of registered asymptomatic individuals undergoing surveillance for PDAC. Individuals without a known...

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PMID: 41740463
DOI: 10.1016/j.ejca.2026.116592

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