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Article

Combating colorectal lung metastases via systemic therapy and thermal ablation: RAS mutation impact.

International journal of surgery (London, England) - 1 Feb 2026

Fan Hongjie, Xu Tao, Zeng Yulan, Hu Jihong, Ding Rong, Li Xinghai, Zhao Fenhua, Fu Chunlong, Cun Jiangping, Li An, Xie Xuancheng, Xu Shufeng, Zou Jiahua, Tang Bufu, Xia Xiangwen

Abstract excerpt

BACKGROUND: To investigate the prognostic value of RAS mutation status and subtypes in colorectal lung metastases (CRLM) patients undergoing image-guided thermal ablation (IGTA), and to evaluate survival outcomes under different systemic therapy regimens. MATERIALS AND METHODS: In this multicenter retrospective-prospective cohort study, 387 patients with CRLM who received percutaneous IGTA between March 2014 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41731873
DOI: 10.1097/JS9.0000000000004089

Genes

KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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