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Real-World Genomic Landscape of Korean Gastric Cancer: Integrating Biomarker Associations and Clinical Outcomes in Metastatic Gastric Cancer.

JCO precision oncology - 1 Feb 2026

Yoo Seong-Keun, Ahn Soomin, Hwang Jinha, Kim Jongwu, Go Yunjin, Kwon Minsuk, Lim Sung Hee, Kim Seung Tae, Kim Kyoung-Mee, Lee Jeeyun

Abstract excerpt

PURPOSE: This study aimed to characterize the genomic landscape of Korean gastric cancer and evaluate associations among oncogenic alterations, established biomarkers, demographics, and treatment outcomes. METHODS: A total of 1,283 patients with gastric cancer who underwent tumor-only targeted sequencing as part of practice and received palliative treatment between January 2017 and August 2025 at the Samsung...

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Aged
Biomarkers, Tumor
CCNE1 gene
Genomics
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Metastasis

Republic of Korea

Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 41712871
DOI: 10.1200/PO-25-01090
PMCID: PMC12931878

Genes

PIK3CA
ARID1A
ERBB2
KRAS
TP53
BCOR
CCNE1
CDKN2A
FGFR2
MET
MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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