Cognitive and motor dual task costs reveal distinct gait impairment phenotypes in Parkinson's disease.

doi:10.1016/j.parkreldis.2026.108203

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Article

Cognitive and motor dual task costs reveal distinct gait impairment phenotypes in Parkinson's disease.

Parkinsonism & related disorders - 1 Mar 2026

Wang Yu, Wang Suyue, Mei Jianing, Zhou Yang, Tang Yunzhe, Wei Zijun, Tao Qingliang, Han Xueyi, Hu Jiyuan, Shi Yuhu, Zhang Yunyun

Abstract excerpt

BACKGROUND: The clinical phenotypes and determinants of heterogeneous dual task gait impairment in Parkinson's disease (PD) remain unclear. We aimed to identify subtypes of dual task gait impairment in PD by comparing cognitive and motor dual task costs (DTC) and to elucidate their independent clinical correlates. METHODS: This multicenter, cross-sectional study enrolled 268 PD patients. Participants underwent...

Topics

Humans
Dual-Task Tests
Parkinson Disease
Female
Male
Cross-Sectional Studies
Gait Disorders, Neurologic
Aged
Phenotype
Middle Aged
Psychomotor Performance
Cognitive Dysfunction
Executive Function

Source

Open in PubMed

Identifiers

PMID: 41619525
DOI: 10.1016/j.parkreldis.2026.108203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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