Article
Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?
Expert opinion on therapeutic targets - 1 May 2014
Chiricozzi Andrea, Saraceno Rosita, Chimenti Maria Sole, Guttman-Yassky Emma, Krueger James G
Abstract excerpt
INTRODUCTION: Psoriasis is a chronic inflammatory skin disorder determined by the activation of several immune cells and resident tissue cells. Various cytokines mediate inflammatory signals, including IL-23, which is an important factor involved in the differentiation of T helper (Th17) cells. AREAS COVERED: Increasing evidence suggests that IL-23 is a central cytokine to the pathogenesis of psoriasis. An...
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