Association of ABCG2 gene variants with urate levels in Mexican patients with type 2 diabetes and chronic kidney disease.

doi:10.1038/s41598-026-35853-3

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Association of ABCG2 gene variants with urate levels in Mexican patients with type 2 diabetes and chronic kidney disease.

Scientific reports - 18 Feb 2026

Mendoza-Carrera Francisco, Vázquez-Rivera Gloria Elizabeth, Gómez-García Erika Fabiola, Parra-Michel Renato, Orozco-Sandoval Rosalba, González-Ramírez Andrea Carolina, Rizo-de la Torre Lourdes Del Carmen, Farías-Basulto Alfonso, Leal-Cortés Caridad Áurea

Abstract excerpt

The contribution of ABCG2 gene variants to hyperuricemia in Mexican patients with type 2 diabetes (T2D) remains uncertain, despite previously established associations in other populations. In this study, we analyzed the association of the ABCG2 gene variants rs2054576, rs2231142 and rs1001796 with serum uric acid (SUA) levels and hyperuricemia in patients with T2D and chronic kidney disease (CKD) from Mexico....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

ATP Binding Cassette Transporter, Subfamily G, Member 2

Cross-Sectional Studies

Diabetes Mellitus, Type 2

Hyperuricemia

Mexico

Neoplasm Proteins

Renal Insufficiency, Chronic

Uric Acid

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Identifiers

PMID: 41708670
DOI: 10.1038/s41598-026-35853-3
PMCID: PMC13013672

Genes

ABCG2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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