Article
Revisiting HLA-DQA1*05 in Asian inflammatory bowel disease cohorts: Ethnic variations in genetic susceptibility to immunogenicity.
World journal of gastroenterology - 7 Feb 2026
Hu Chao-Qun, Song Xiao-Mei, Teng Yong-Sheng, Guo Hong
Abstract excerpt
We read with great interest the article by Weng et al, wherein the authors investigated human leukocyte antigen (HLA) alleles linked to anti-drug antibody (ADA) formation in Taiwanese patients with inflammatory bowel disease. They reported that HLA-DQA1*05, a major risk allele in European cohorts, demonstrated no association with ADA development in Taiwanese patients. Instead, novel alleles emerge: HLA-C*03:04:01...
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