Article
Targeting the immunogenetic diseases with the appropriate HLA molecular typing: critical appraisal on 2666 patients typed in one single centre.
BioMed research international - 1 Jan 2013
Guarene M, Capittini C, De Silvestri A, Pasi A, Badulli C, Sbarsi I, Cremaschi A L, Garlaschelli F, Pizzochero C, Monti M C, Montecucco C, Corazza G R, Larizza D, Bianchi P E, Salvaneschi L, Martinetti M
Abstract excerpt
We compared the immunogenetic data from 2666 patients affected by HLA-related autoimmune diseases with those from 4389 ethnically matched controls (3157 cord blood donors CBD, 1232 adult bone marrow donors BMD), to verify the appropriateness of HLA typing requests received in the past decade. The frequency of HLA-B∗27 phenotype was 10.50% in 724 ankylosing spondylitis, 16.80% in 125 uveitis (3.41% BMD, 4.24% CBD,...
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