Article
Deciphering the role of endolysin LysCPD7 harboring C. perfringens spore binding domain.
Microbiological research - 1 Jun 2026
Ha Eunsu, Shin Daeun, Ryu Sangryeol, Kong Minsuk
Abstract excerpt
Due to their potent bactericidal activity, phage-derived endolysins are considered promising alternatives to conventional antibiotics. Although some endolysins from phages infecting spore-forming bacteria contain a spore binding domain (SBD), their biological function remains unclear. LysCPD7, an endolysin from the Clostridium perfringens phage CPD7, showed high antimicrobial activity, effectively reducing C....
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