Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic studies of psychosocial disability establish correlations and causal relationships with neuropsychiatric disorders.

Psychiatry research - 1 Apr 2026

Doherty Evie, Laighneach Aodán, Casburn Mia, Quilligan Fergus, Donohoe Gary, Cannon Dara M, Morris Derek W

Abstract excerpt

Psychosis is a clinically heterogenous disorder associated with significant difficulties with social and occupational function (psychosocial disability; PD). While environmental and cognitive factors are identified predictors of PD, the genetic contribution remains unclear. Here, we investigated the hypothesis that objective social participation (SP) and occupational engagement are genetically influenced. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Employment
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Psychotic Disorders

Share to Schizophrenia

Share to UK Biobank

Share to United Kingdom

Source

Identifiers

PMID: 41690028
DOI: 10.1016/j.psychres.2026.116963

Genes

CDH7
CSE1L
DDX27
DRD2
GBE1
STAU1
TCF4
ZNF536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic studies of psychosocial disability establish correlations and causal relationships with neuropsychiatric disorders.PMID 41690028Read ↗

Genome-wide association studies of social participation and occupational engagement in the UK BiobankSemantic proximity Read ↗

Genetic overlap with schizophrenia and Parkinson's reveals psychomotor basis of physical activitySemantic proximity Read ↗

Schizophrenia genetic risk and labour market outcomes in the Finnish general population: Are schizophrenia-related traits penalised or rewarded?Semantic proximity Read ↗

Genome-wide association study of occupational attainment as a proxy for cognitive reserve.Semantic proximity Read ↗

Genome-wide Cox regression analysis identifies 134 novel risk loci for disability development: the Canadian Longitudinal Study on Aging and UK Biobank.Semantic proximity Read ↗

Genetic variations underlying self-reported physical functioning: a review.Semantic proximity Read ↗

Polygenic prediction of occupational status GWAS elucidates genetic and environmental interplay in intergenerational transmission, careers and health in UK Biobank.Semantic proximity Read ↗

Polygenic risk score for disability and insights into disability-related molecular mechanisms.Semantic proximity Read ↗

Multidimensional social inclusion and its prediction in schizophrenia spectrum disorderSemantic proximity Read ↗

The brain network underlying social participation: a multimodal, data-driven investigation.Semantic proximity Read ↗

Genome-wide association analyses using machine learning-based phenotyping reveal genetic architecture of occupational creativity and overlap with psychiatric disorders.Semantic proximity Read ↗

A genome-wide association study of occupational creativity and its relations with well-being and career success.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.