Article
Genome-wide association analyses using machine learning-based phenotyping reveal genetic architecture of occupational creativity and overlap with psychiatric disorders.
Psychiatry research - 1 Mar 2024
Kim Hyejin, Ahn Yeeun, Yoon Joohyun, Jung Kyeongmin, Kim Soyeon, Shim Injeong, Park Tae Hwan, Ko Hyunwoong, Jung Sang-Hyuk, Kim Jaeyoung, Park Sanghyeon, Lee Dong June, Choi Sunho, Cha Soojin, Kim Beomsu, Cho Min Young, Cho Hyunbin, Kim Dan Say, Jang Yoonjeong, Ihm Hong Kyu, Park Woong-Yang, Bakhshi Hasan, O Connell Kevin S, Andreassen Ole A, Kendler Kenneth S, Myung Woojae, Won Hong-Hee
Abstract excerpt
Creativity is known to be heritable and exhibits familial aggregation with psychiatric disorders; however, the complex nature of their relationship has not been well-established. In the present study, we demonstrate that using an expanded and validated machine learning (ML)-based phenotyping of occupational creativity (OC) can allow us to further understand the trait of creativity, which was previously difficult...
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