Quantitative genetics of natural S. cerevisiae strains upon mating reveal heritable determinants of fitness and differential mating affinities.

doi:10.1016/j.celrep.2026.116972

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Article

Quantitative genetics of natural S. cerevisiae strains upon mating reveal heritable determinants of fitness and differential mating affinities.

Cell reports - 24 Feb 2026

Strauss Sivan Kaminski, Golomb Ruthie, Khoury Donya, Aharon-Hefetz Noa, Meyer Hadar, Sheykhkarimli Dayag, Liti Gianni, Dahan Orna, Pilpel Yitzhak

Abstract excerpt

Among the fundamental questions in sexual reproduction are how fitness is inherited and whether parents exhibit differential mating affinities. Addressing these questions requires quantitative genetic tools and large phenotyped and genotyped strain collections from a single species. We leverage sexual mating among nearly 100 natural isolates of Saccharomyces cerevisiae, generating thousands of offspring across...

Topics

Saccharomyces cerevisiae
Genetic Fitness
Reproduction
Glycerol
Phenotype
Genes, Mating Type, Fungal
Glucose

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Open in PubMed

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PMID: 41689801
DOI: 10.1016/j.celrep.2026.116972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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