Article
Genetic diversity and haplotype structure of the CelTOS gene in Plasmodium falciparum from Jazan Province, Saudi Arabia: implications for vaccine development and malaria elimination.
Frontiers in cellular and infection microbiology - 1 Jan 2025
Alothaid Hani, Alghnnam Fatimah, Al-Qahtani Arwa A, Al Marzan Abdullah, Abu Alola Mashael, Bohol Marie Fe F, Alhamlan Fatimah, Shafeai Mohammed I, Rudiny Fuad H, Motaen Ali M, Al-Qahtani Ahmed A
Abstract excerpt
Background: Malaria remains a persistent health challenge in southern Saudi Arabia, particularly along the border with Yemen. Understanding the genetic diversity and population structure of Plasmodium falciparum antigens is essential for tracking transmission dynamics and informing vaccine design. This study characterises population genetics of the Cell-Traversal Protein for Ookinetes and Sporozoites (CelTOS)...
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