Association of Single-Nucleotide Polymorphisms in Sweet Taste Perception and Intake Genes with Primary Ciliary Dyskinesia and Its Clinical Phenotypes.

doi:10.3390/ijms27031234

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Article

Association of Single-Nucleotide Polymorphisms in Sweet Taste Perception and Intake Genes with Primary Ciliary Dyskinesia and Its Clinical Phenotypes.

International journal of molecular sciences - 26 Jan 2026

Piatti Gioia, Aldè Mirko, Ruberto Romina, Santin Aurora, Girotto Giorgia, Concas Maria Pina

Abstract excerpt

Primary ciliary dyskinesia (PCD) is a congenital motile ciliopathy causing impaired mucociliary clearance and characterized by recurrent respiratory infections affecting both the upper and lower airways. Several genes involved in taste perception pathways are expressed in extraoral tissues and have recently emerged as regulators of airway immune responses. This study aimed to (1) analyze potential correlations...

Topics

Humans
Polymorphism, Single Nucleotide
Female
Male
Adult
Adolescent
Middle Aged
Child
Gene Frequency
Phenotype
Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Young Adult

Taste Perception

Ciliary Motility Disorders

Genetic Predisposition to Disease

Alleles

Fibroblast Growth Factors

Genetic Association Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 41683661
DOI: 10.3390/ijms27031234
PMCID: PMC12897696

Genes

FGF21
SLC2A4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-41683661-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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