Article
Four Gene Polymorphisms as Potential Predictive Biomarkers for Lung Cancer Susceptibility and Therapeutic Response in Iraqi Patients: A Pharmacogenetic Case-Control Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Feb 2026
Orabiy Mohammed Ouda, Chyad Doaa Hadi, Hoidy Wisam Hindawi
Abstract excerpt
BACKGROUND: Lung cancer remains the leading cause of cancer-related deaths worldwide, with limited genetic data available on Middle Eastern populations. This study investigated four novel genetic variants CYPHER rs7834621, METOX1 rs9284659, DRUGRES2 rs4521739, and TOXMET3 rs8823471 for their association with lung cancer risk and treatment response in Iraqi patients. METHODS: Between January 2024 and September...