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Article

Systemic inflammation is a risk factor for oral health: an analysis of data from the UK Biobank.

Frontiers in immunology - 1 Jan 2025

Berger Martin, Kern Jaana-Sophia, Schulze-Späte Ulrike, Wolfart Stefan, Jankowski Joachim, Wolf Michael, Marx Nikolaus, Marx-Schütt Katharina

Abstract excerpt

Background: Oral health has been implicated as a contributor to systemic inflammation and cardiovascular disease. However, the reverse relationship-whether systemic inflammation causally affects oral health-remains poorly defined. This study investigates the directional role of systemic inflammation in oral disease using genetic and phenotypic data from the UK Biobank. Methods: We analyzed data from 468,460 UK...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41660612
DOI: 10.3389/fimmu.2025.1651947
PMCID: PMC12872472

Genes

IL6R

Variants

rs2228145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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