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Article

Genetic evidence for causal link between systemic inflammation and dental caries risk: A bidirectional Mendelian randomization study.

Medicine - 31 Jul 2026

Xu Zhe, Liu Xiaofen, Lei Fengzhen, Hu Ziyang, Shi Ping

Abstract excerpt

The causal relationship between systemic inflammation and dental caries remains unclear. This study aimed to investigate the bidirectional causal association between circulating cytokines and the risk of dental caries. A bidirectional 2-sample Mendelian randomization (MR) study was conducted. Genetic instruments for 132 circulating cytokines were obtained from 2 large-scale genome-wide association study consortia...

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Share to Chemokine CCL5
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42536563
DOI: 10.1097/MD.0000000000050025
PMCID: PMC13433123

Genes

CXCL9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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