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Article

Association between 1400 blood metabolites and the risk of ankylosing spondylitis: A 2-stage, 2-sample Mendelian randomization study.

Medicine - 6 Feb 2026

Li Fei, Zhou Xinhua, Li Chunning, Zhang Zhenfeng, Yang Qiqi

Abstract excerpt

Human blood metabolites have been closely linked to ankylosing spondylitis (AS) in observational studies, yet direct causal evidence remains limited. This study aims to use Mendelian randomization (MR) to pinpoint causal metabolites associated with AS and to predict potential side effects of metabolite interventions. Genetic instruments for exposure were sourced from a genome-wide association study of 1400 blood...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41650064
DOI: 10.1097/MD.0000000000047598
PMCID: PMC12885695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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