Article
Divergent and overlapping roles of homospermidine and spermidine in Sinorhizobium meliloti physiology and symbiotic performance.
Microbiology (Reading, England) - 1 Feb 2026
Becerra-Rivera Víctor A, Ide Alejandra Arteaga, Reyes-González Alma R, Dunn Michael F
Abstract excerpt
Unlike most rhizobia, Sinorhizobium meliloti produces spermidine (Spd) in addition to putrescine (Put) and homospermidine (HSpd) as soluble intracellular polyamines. To investigate their roles, we analysed S. meliloti Rm8530 mutants lacking hss (homospermidine synthase, smc04016) or casdh (carboxyspermidine dehydrogenase, smb21630), as well as a double mutant. Biochemical and phenotypic characterization confirmed...
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