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High frequency of isoniazid and fluroquinolone resistance among patients with rifampicin sensitive tuberculosis.

Diagnostic microbiology and infectious disease - 1 Feb 2024

Jain Parul, Ratnam Rashmi, Sengupta Senjuti, Singh Urmila, Kumar Vijay, Jain Amita

Abstract excerpt

This study was done to determine frequency of isoniazid (INH) and fluoroquinolones FQ resistance among rifampicin sensitive strains of Mycobacterium tuberculosis and to study their mutation patterns. Retrospective analysis was done for samples with M. tuberculosis detected by Cartridge based NAAT (CBNAAT). They were tested sequentially by first line (FL) and second line - line probe assay (SL-LPA) depending on...

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PMID: 38101237
DOI: 10.1016/j.diagmicrobio.2023.116159

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