Article
Development and preliminary assessment of the iFIND TBR: all-in- one molecular diagnostic assay for rapid detection of Mycobacterium tuberculosis and rifampicin resistance.
Frontiers in cellular and infection microbiology - 1 Jan 2024
Ou Xichao, Song Zexuan, Xing Ruida, Zhao Bing, Pei Shaojun, Teng Chong, Zhang Lincai, Sun Qian, Liu Fang, Xia Hui, Zhou Yang, Zheng Yang, Song Yuanyuan, Zhang Zhiguo, Wang Shengfen, Anthony Richard, Zhao Yanlin
Abstract excerpt
Introduction: Early and accurate diagnosis of tuberculosis (TB) is crucial for initiating timely treatment and preventing new infections. In this study, we introduced the iFIND TBR assay, an automated all-in-one tuberculosis detection approach that simultaneously detect Mycobacterium tuberculosis (MTB) and rifampicin (RIF) resistance. Methods: The limits of detection (LOD), sensitivity, specificity, and RIF-R...
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